Dr. Clayton C. Yates

Clayton C. Yates, Ph.D.
Department of Biology and Center for Cancer Research
Tuskegee University, Tuskegee AL 36088
Phone:   (334 ) 727-8949 
Email:  cyates@mytu.tuskegee.edu 


2005      Doctor of Philosophy, Dept. of Pathology University of Pittsburgh School of Medicine - Pittsburgh, PA 15261
2005      Certification in Tissue Engineering University of Pittsburgh School of Medicine - Pittsburgh, PA 15261
2001      Masters of Science  Dept of Biology Tuskegee University – Tuskegee, AL 36088
1998      B.S. in Biology Tuskegee University – Tuskegee, AL 36088

Selected Publications:

1.  A Wells, S Kharait, C Yates, L Satish (2004). Calpain proteases in prostate carcinomas. In Immunohistochemistry and In Situ Hybridization of Human Carcinomas, volume 1 (Ed: MA Hayat, Elsevier Science/Academic Press).

2.   C Yates, DB Stolz, LG Griffith (2005). Imaging Invasion and Metastasis ex vivo. In Cell Motility in Cancer Invasion and Metastasis (Ed: A Wells, Kluwer Academic Press, Amsterdam).

3.   Sourabh Kharait, Kien Tran, Clayton Yates and Alan Wells (2005) Cell Motility in Prostate Tumor invasion and metastasis. In Cell Motility in Tumor Progression (ed: A Wells). Kluwer Academic Publishers (Amsterdam).

4. Yates C, Wells A, Turner T. Luteinising hormone-releasing hormone analogue reverses the cell adhesion profile of EGFR overexpressing DU-145 human prostate carcinoma subline. British journal of cancer 2005;92:366-75. PMID: 15655536

5.   Yates C, Shepard CR, Papworth G, Dash A, Beer Stolz, Tannenbaum S, Griffith L, Wells A. (2007) “Direct Visualization of Prostate Cancer Progression utilizing a Novel Organotypic Liver Bioreactor as Metastatic Target Organ”. Advances  in Cancer Research .2007;97:225-466.   PMID: 17419948

6.  Yates C, Shepard CR, Stolz DB, Wells, A  (2007) “Co-culturing human prostate carcinoma cells with hepatocytes lead to increased expression of E-cadherin”.  Br J Cancer.  Apr 23;96 (8):1246-52. PMID: 17406365

7. Ritu Aneja, Jun Zhou, Clayton Yates,  Binfei Zhou, Surya N. Vangapandu Harish C. Joshi  “Multidrug Resistance-Associated Protein – OverexpressingTeniposide-Resistant Human Lymphomas Undergo Apoptosis by a Tubulin-Binding Agent.” Cancer Res. 2008 Mar 1;68(5):1495-503.  PMID: 18316614

8. Alan Wells, Clayton Yates, Christopher Shepard. (2008) “E-cadherin as an indicator of mesenchymal to epithelial reverting transitions during the metastatic seeding of disseminated carcinomas”.  Clinical Experimental Metastasis July 4: 25(6): 621-628 PMID: 18600305

9. Karna, P., S. M. Sharp, Yates, C, Aneja R. (2009). "EM011 activates a survivin-dependent apoptotic program in human non-small cell lung cancer cells." Mol Cancer 8: 93. PMID: 19878573

10. Mohamed O. Abdalla, Ritu Aneja, Derrick Dean, Vijay Rangari, Albert Russell Jessie Jaynes, Clayton Yates  and Timothy Turner  (2010) Synthesis and characterization of noscapine loaded magnetic polymeric nanoparticles” Journal of Magnetism and Magnetic Materials  Volume 322, Issue 2,  p 190-196 PMID: 20161408

11. Sajni Josson, Starlette Sharp, Ritu Aneja, Ruoxiang Wang, Timothy Turner, Leland W.K Chung, Clayton Yates “Tumor-Stromal Interactions Influence Radiation Sensitivity in Epithelial- versus Mesenchymal-Like Prostate Cancer Cells,” Journal of Oncology, vol. 2010, Article ID 232831, 10 pages, 2010. PMID: 20798867

12. Shaniece Theodore, Timothy Turner, Johng Rhim, Clayton Yates (2010) “miRNA 26a Expression in a Novel Panel of African American Prostate Cancer Cell Lines”.  Ethnicity and Disease Volume 20, Supp 1, Pages S1-96-100 PMID: 20521394

13.  Ritu Aneja, Tohru Miyagi, Clayton Yates, Leland W. K. Chung, and Harish C. Joshi Non-toxic treatment of hormone-refractory prostate cancer in mice” European Journal of Cancer  Volume 46Issue 9, Pages 1668-1678 (June 2010) PMID: 20303260

14.   Sajni Josson, Cynthia S. Anderson, Shian-Ying Sung, Peter A. S. Johnstone, Hiroyuki Kubo, Chia-Ling Hsieh, Rebecca Arnold, Murali Gururajan, Clayton Yates, and Leland W. K. Chung “ Inhibition of ADAM9 expression induces epithelial phenotypic alterations and sensitizes human prostate cancer cells to radiation and chemotherapy”  Prostate. 2011 Feb 15;71(3):232-40

15. C. Yates*, S. Sharp, J. Jones, D.Topps, M. Coleman, R. Aneja, J.Jaynes, T.Turner, “LHRH-conjugated lytic peptides directly target prostate cancer cells”. Biochem Pharmacol. 2011 Jan 1;81(1):104-10. (*corresponding author)

16. Shaniece Theodore, Star Sharp, Jianjun Zhou, Timothy Turner, *Clayton Yates, *Johng Rhim . “Establishment of a Novel non-malignant and malignant cell line paired cell line from African American Prostate Cancer Patient” Int J Oncol. 2010 Dec;37(6):1477-82. PMID:21042716  (*corresponding author)

17.  Timothy Turner, Stephen Sodeke, Vivian Carter, Will Tarver, Isaac Mwase and Clayton Yates “Your Prostate, Your Life,” African American Prospectives  (Sept 2010 issue), p32-35 ISSN 1948-0946

18. Mohamed O. Abdalla, Prasanthi Karna, Hari Krishna Sajja, Hui Mao, Clayton Yates, Timothy Turner, Ritu Aneja, “Enhanced noscapine delivery using uPAR-targeted optical-MR imaging trackable nanoparticles for prostate cancer therapy”  J Control Release. 2011 Feb 10;149(3):314-22.

19. R. Renee Reams, Krishna Rani Kalari, Honghe Wang, Folakemi T. Odedina, Clayton Yates “ Detecting gene-gene interactions in prostate disease in African American men”  Infectious Agents and Cancer 2011 6(Suppl 2):S1.  doi:10.1186/1750-9378-6-S2-S1

20.  Jianjun Zhou, Honghe Wang, Virginetta Cannon, Karen Marie Scott, Hongbin Song, Clayton Yates “Side population rather than CD133+ cells distinguishes enriched tumorigenicity in hTERT-immortalized primary prostate cancer cell”  Molecular Cancer  2011 Sep 14;10(1):112. PMID: 21917149  [Highly Accessed]